Friday 22 October 2010

Candida and Yeast Genome Databases and OrthologID

The full Candida Genome Database can be found here:  http://www.candidagenome.org/

Search the genome and view/download sequences.  Read the tutorials on Gene Ontology - which describes the complete biology of individual gene products in any organism...

Other strains also available:

  • Candida albicans WO-1
  • Candida dubliniensis CD36
  • Candida glabrata CBS138
  • Candida guilliermondii ATCC 6260
  • Candida lusitaniae ATCC 42720
  • Candida parapsilosis CDC 317
  • Candida tropicalis MYA-3404
  • Debaryomyces hansenii CBS767
  • Lodderomyces elongisporus NRLL YB-4239


The Saccharomyces Genome Database can be found here:  http://www.yeastgenome.org/

What I am interested in, is Orthologs... between different species.  Orthologs between the microbe and its host... .. and resources that enable one to compare two or more genomes... Genome Orthology?  I am still in Year 2 level biology (at the age of 40 and after 20+ years interest)... but I see potential in comparing the ontologies of genes in different genomes...

Isolation and characterization of human orthologs of yeast CCR4–NOT complex subunits
http://nar.oxfordjournals.org/content/28/3/809.full

Orthology between genomes of Brachypodium, wheat and rice
http://www.biomedcentral.com/1756-0500/2/93

OrthologID: automation of genome-scale ortholog identification within a parsimony framework

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